The short-term effects of benzoyl peroxide lotion on the resolution of inflamed acne lesions

A double blind study carried out in two centres showed that a 5% benzoyl peroxide lotion†† Topex Acne Lotion (U.K.), Mytolac (Europe), Richardson-Merrell Ltd, Egham, Surrey. used topically for only 5 days significantly reduced the number of inflamed acne lesions. The possibility that such a rapid resolution of acne lesions may be due to an antibacterial or a direct effect on mediators of inflammation is discussed.