不育
旁分泌信号
自分泌信号
免疫系统
生物
细胞因子
泌尿生殖系统
男性不育
生育率
生殖免疫学
免疫学
生理学
医学
生殖技术
怀孕
人口
遗传学
解剖
细胞培养
哺乳期
受体
环境卫生
作者
Monika Frączek,Maciej Kurpisz
标识
DOI:10.1016/j.jri.2015.02.001
摘要
Cell integration between the immune and reproductive systems is the basis for normal male reproductive physiology. Cytokines are a part of the autocrine/paracrine network operating in the male reproductive tract. At the same time, immunological reactions occurring via cytokines appear to be both beneficial and/or risk factors for male fertility. As the cytokines are produced by a whole spectrum of cells in all compartments of the male genital tract, they can also be involved in a variety of andrological disorders. The monitoring of cytokines and other immune factors in seminal plasma may offer a chance to better understand the mechanisms leading to sub-/infertility. In this review, we present insights into cytokine interplay in some of the pathological conditions associated with male reproduction.
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