多导睡眠图
医学
判别式
睡眠呼吸暂停
功能连接
脑电图
呼吸不足
物理医学与康复
心脏病学
呼吸暂停
内科学
神经科学
心理学
计算机科学
机器学习
精神科
作者
Tingting Zhang,Yu Pan,Jian-Ping Lian,Feng Pang,Jinfeng Wen,Yuxi Luo
出处
期刊:Physiological Measurement
[IOP Publishing]
日期:2021-07-01
卷期号:42 (7): 075004-075004
被引量:9
标识
DOI:10.1088/1361-6579/ac0e83
摘要
Objective. Sleep apnea hypopnea syndrome (SAHS) induces abnormalities in brain function. This study aims to find features that can characterize the impact of SAHS on the brain functional connectivity (FC) during sleep.Approach. Seventy-eight participants (39 SAHS patients and 39 age-matched healthy controls) were recruited and underwent a whole night of polysomnography. The improved weighted phase lag index algorithm was utilized to evaluate FC inδ,θ,α,β, andγbands of six EEG channels. The regional FC features were further constructed to characterize the asymmetries of FC between the left and right hemispheres, the imbalances of FC between the inter- and intra-hemispheres, and those between the anterior and posterior cortex, respectively. Then, support vector machines and feature evaluation were used to verify the discriminative ability for the abnormal FC in SAHS patients of the above-mentioned features.Main results.The study observed abnormal FC changes in SAHS patients during sleep in multiple frequency bands. Moreover, regional FC features performed better in SAHS screening, and important features were mainly distributed inβandγbands.Significance. Our research exhibited the abnormal regional FC in SAHS patients during sleep, which provided new insights and established indicators to investigate the changes of brain function in patients.
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