神经科学
海马体
痴呆
发病机制
老年斑
阿尔茨海默病
疾病
针灸科
医学
β淀粉样蛋白
τ蛋白
生物
病理
替代医学
出处
期刊:PubMed
[National Institutes of Health]
日期:2014-03-01
卷期号:34 (3): 359-61
被引量:3
摘要
To discuss the pathogenesis of Alzheimer's disease (AD), we summarized the mechanisms of treating AD animal models by acupuncture from literatures in recent years as follows. Senile dementia rats' cognitive capabilities and memory could be improved by reduction of beta-amyloid protein, attenuation of excessive phosphorylation of tau protein, regulation of center neurotransmitter dysmetabolism, oxidation of anti-free radicals, reduction of neuron apoptosis in the cortex and the hippocampus, inhibition of glial cells' differentiation, adjustment of G protein signaling transduction, and improvement of the mitochondrial dysfunction, thus providing experimental evidence for treating AD by acupuncture.
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