Heme oxygenase-1 expression in alveolar macrophages is elevated in patients with bronchiolitis obliterans syndrome after lung transplantation

In their study, Lu et al 1 Lu F. Zander D.S. Visner G.A. Increased expression of heme oxygenase-1 in human lung transplantation. J Heart Lung Transplant. 2002; 21: 1120-1126 Abstract Full Text Full Text PDF PubMed Scopus (40) Google Scholar showed increased expression of heme oxygenase-1 (HO-1) in alveolar macrophages in lung tissue samples of patients with acute and/or chronic allograft rejection after lung transplantation (LTx). Their study speculated that the increased production of HO-1 in human lung allografts is most likely a beneficial response.