Fault diagnosis technology was an important technology to guarantee the safe operation of railway equipment.It was analyzed the uncertainties traditional locomotive bearing fault diagnosis method,the multisensor information fusion method was applied to make a fault diagnosis,and built the Fusion Fault Diagnosis System.The System used the idea of decision grade fusion to handle these uncertainties.Experimental results showed that this method could effectively solve the Diagnostic System based on a single parameter of the uncertainty.Thus it had great theoretical significance and application value.