Comparison on intrahepatic recurrence of hepatocellular carcinoma after regular hepatectomy and irregular hepatectomy

Objective To compare the intrahepatic recurrence of hepatocellular carcinoma after regular hepatectomy and irregular hepatectomy. Methods One hundred and twenty patients with primary liver cancer undergoing hepatectomy in our department from 2007 to 2012 were selected, which were divided into regular hepatectomy group and irregular hepatectomy group, with 60 patients in each group. General surgery condition, the liver function after six months, the recurrence rate after one year and the survival rate were compared between the two groups. Results The diameter of tumor removed, volume of liver removed, blood loss, blood transfusion, the number of hepatic resection in regular hepatectomy group were significantly higher than those in irregular hepatectomy group, P0.01. Six months after surgery, serum albumin(ALB) was significantly higher in regular hepatectomy group than irregular hepatectomy group, while TBIL, glutamic-pyruvic transaminase(ALT) and total bilirubin(DBIL) were significantly lower(P0.01). The 1-year recurrence rate in regular hepatectomy group was significantly lower than that in irregular hepatectomy group, while 1-year disease-free survival rate and 1-year overall survival rate in regular hepatectomy group were significantly higher(P0.05). Conclusion Although regular hepatectomy results in larger surgical injury, it has the advantages of larger range of resection, better postoperative recovery and lower recurrence rate, which is suitable for clinical applications.