Clinical evaluation of Bio-Oss and Bio-Gide in the treatment of periodontitis with vertical bone resorption

Objective To evaluate the clinical effects of a combined use of Bio-Oss and the Bio-Gide in the treatment of periodontitis with vertical bone resorption.Methods Twenty-eight patients with chronic periodontitis,after initial therapy for 6 weeks,including 40 teeth with vertical bone resorption which pockets depth exceeded 5mm were divided into two groups.Twenty teeth were treated with Bio-Oss and Bio-Gide(GTR group)and 20 teeth with open-flap debridement(control group).Clinical parameters,including attachment loss(AL),pocket depth(PD),bleeding index(BI),plaque index(PLI),gingival recession(GR)and tooth mobility(TM),were evaluated,and the defect of alveolar bone were observed on radiograms preoperatively and 3,6 and 12 months after therapy.Results The GTR group showed significant reduction of PD,CAL and BI after operation compared with pre-operation and the control group(P0.01).The TM in GTR group at 6 and 12 months after operation was significantly decreased compared with the preoperation and the control group.At 3,6 and 12 month PLI became lower than before surgery(P0.05).The control group PD and BI were decreased compared with preoperation.AL was slightly lower than preoperation.GR and tooth mobility degree showed no significant differences before and after surgery.Conclusion Bio-Oss and Bio-Gide can significantly reduce periodontal pocket depth and promote new attachment and new bone formation.