The impurities generated from the preparation process of acrylamide greatly effected on the properties of polyacrylamide.Researches showed that reducing the impurities containing in monomers was necessary to obtain polyacrylamide with satisfactory quality.In this article,experimental results were showed that impurities containing in acrylamide were reduced effectively by optimizing the parameters of equipment and technology and improvement of refining during the production of both acrylonitrile and acrylamide.The experimental polymerization of acrylamide showed that the new acrylamide produced after technology optimization can be used to synthesize polyacrylamide with high quality.