The compressibility data for 9 crude oil samples at 308-338 K,and 0.6-6.6 MPa were measured by using PVT device made by RUSKA corporation.The densities for 9 oil samples at different temperatures were also obtained.The experimental data shows that the oil compressibility increases with the increasing of temperature and the decreasing of pressure.Correlation for isothermal oil compressibility was developed as a function of temperature,pressure and density data.The average error for 404 compressibility data was only 2.96%.The correlation can be used to predict the oil compressibility at other operation conditions during the calculation and design of crude oil in transportation.