Intestinal originated infection of pancreas in acute pancreatitis and its managements

In recent years, the importance of the secondary infection originated from intestines in acute pancreatitis has been acknowledged and established. When the intestinal barrier is damaged in acute pancreatitis, the indigenous bacteria, fungi and endotoxin in the bowel are translocated to the extraintestinal tissues and organs,which consequently promote the process of the acute pancreatitis. The author reviewed the mechanisms of the intestinally originated infection, the routes of the bacteria translocation and its managements.