Objective To study the effect of sclera dencleis is to treatment of refractory glaucoma. Methods 28 cases (28 eyes) refractyroy glaucoma were diagnosed . The were neovascular glaucoma in 16 eyes,non_lens glaucoma in 3 eyes,and 9 eyes had accepted twice or more trabeculectomy.All eyes were high intraocular pressu re (39.38~84.32 mmHg,average 55.42 mmHg).The situation of intraocular pressure, UBM and silit_lamp were observed after operation. Results After operation ,16 cases were followed up for more th a n 12 months,10 cases for 6~12 months,and 2 cases were not followed up. Iris neo v ascular were disappeared after operation in all neovascular glaucoma cases. The p ostoperative pressure was ≤30 mmHg in all cases,and ≤21 mmHg was 86%. 5eyes oc curred detachment of choroid and cured by using medicine. Conclusion Sclera dencleisis is an effective surgical method t o therapy refractory glaucoma.