The ability of tactile perception is essential for intelligent prosthetic hands to perform complex operations and achieve friendly external interaction, but is still a challenge to achieve. In article number 1900317, Ziwei Liang, Xue Feng and co-workers propose a new kind of high-performance flexible tactile sensor enabling intelligent tactile perception for soft prosthetic hands (SPD). The smart SPD completes various complicated tasks like a real hand. All of these have demonstrated the promising applications of soft prosthetic hands with sense of touch in robotics, artificial limbs and medicine.