Perspective Chapter: Magnetoliposomes - A Recent Development as Recent Advances in the Field of Controlled Release Drug Delivery

作者
Edyta Maroń,Paweł Krysiński,M. Chudy
出处
期刊:IntechOpen eBooks [IntechOpen]
被引量:1
标识
DOI:10.5772/intechopen.106348
摘要

The authors of this chapter point out that, although liposomal vesicles are widely used in cancer drug delivery systems, their limitations are also known. Therefore, more recently, new developments in modifications of liposomes have rapidly appeared to improve their parameters, including the maintenance of drugs in their structure, accumulation in target sites, and the active mechanism of drug release. Research on the effectiveness of existing liposomal carriers through their functionalization, allowed to propose a promising candidate for multifunctional nanoplatform based on liposomes and magnetic nanoparticles called magnetoliposomes. The presence of magnetic nanoparticles makes it possible to magnetically direct the liposomal carrier to the specific site, and appropriate magnetic field parameters can lead to controlled disintegration of the vesicle and release of the drug. The increasing variety of suggested platforms constantly provides new variants in the structure and mechanism of drug release, which enable the adjustment of the carrier’s characteristics to the specific needs of cancer therapy.

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