Advances in the Study of Selenium‐Enriched Probiotics: From the Inorganic Se into Se Nanoparticles

Abstract Selenium (Se) is a momentous metallic element that plays an irreplaceable role in biochemical activities. Se deficiency remains a nutritional challenge across the world. Organic Se supplementation is the most effective treatment means for Se deficiency. Organic Se transformed from Se‐enriched probiotics show outstanding excellent properties in antibacteria, anti‐oxidation, anti‐inflammation, and immunoregulation. Studying the influencing factors for Se enrichment capacity and enrichment mechanisms of Se‐enriched probiotics is conducive to the exploit of more potent Se‐enriched probiotics. Se‐enriched probiotics transform inorganic Se into Se nanoparticles (SeNPs), which have been widely used in animal husbandry and biomedical field. In this paper, the novel development of Se‐enriched probiotics is reviewed, and the bioactivities of SeNPs are assessed, so as to display their potential application prospects. The excellent role of SeNPs in anti‐oxidation is summarized, and the mechanism by which SeNPs improve Se deficiency and boost animal health is explained.