Chemical composition and nutritional properties of Gastrodia elata water extract and its effects in rats with streptozotocin–induced diabetic osteoporosis

The protective effect of WGE against diabetic osteoporosis arises from several mechanisms: lowering blood glucose levels, inhibiting oxidative stress and inflammation, and modulating OPG/receptor activator of nuclear factor-κB ligand (RANKL) expression. Our results indicated that WGE could serve as a theoretical foundation for the treatment of diabetic osteoporosis.