阳离子聚合
支柱
化学
静电学
笼子
批评
结晶学
纳米技术
高分子科学
高分子化学
材料科学
物理化学
法学
数学
结构工程
组合数学
工程类
政治学
作者
Syed Tousif Ahmed,Eduardo Anaya‐Plaza,Ngong Kodiah Beyeh,Mauri A. Kostiainen
标识
DOI:10.1002/chem.202202022
摘要
Our recent publication in Chem. Eur. J. 2022, 28, e202104341 has inspired Prof. Peter B. Crowley (P.C.) to write a Correspondence questioning the presented concept of electrostatic self-assembly. The offered criticism is twofold: 1) the role of the cationic pillar[5]arene macrocycle to act as molecular glue in the formation of electrostatically driven protein assemblies is questioned by arguing that the pillararene is not incorporated into the frameworks. 2) Later, P.C. speculates that when the frameworks form, the role of electrostatic interactions is not firmly established and cation-pi bonding is the more plausible interaction. In this response, the raised comments are addressed. We present direct experimental NMR evidence showing that the pillar[5]arene is incorporated into the frameworks. Furthermore, we discuss the electrostatic self-assembly and our ferritin-related research line more broadly and clarify the role of key experiments.
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