Mepolizumab for severe eosinophilic asthma

Personalized medicine is an emerging field in treatment of severe eosinophilic asthma with the development of biologic agents. Mepolizumab has shown significant benefits in patients with severe eosinophilic asthma (reducing asthma exacerbations, improving quality of life and lung function), while remission has emerged as a treatment goal in some patients. The impact of mepolizumab in airway remodeling suggests its use as a disease modifying therapy not just as a symptom controller.