Divergent Total Syntheses of Elisapterane and Relevant Diterpenoids Assisted by In Silico Structure Reassignment

-elisabanolide. By integrating our inference aided by computational tools with validation through total synthesis, this work exemplifies a modern case of total synthesis detective stories, demonstrating the power of computer-assisted structure elucidation (CASE) and the risks of analogical approaches for the structure assignment of natural products.