NHC‐Activations on α‐, β‐, γ‐, and Beyond

Abstract Over the recent decades, due to the special electronic characteristics and diverse reactivities, N‐heterocyclic carbene (NHC) has received significant interest in organocatalyzed reactions. The formation of Breslow intermediates by NHC can convert into acyl anion equivalent, enolates, homoenolate, acyl azolium, and vinyl enolate etc ., and the cycloaddition reactions of these species has attracted lots of attention. In this review, we focus on the summry of the development of NHC‐activation of carbonyl carbon (or imine carbon) in situ , α‐, β‐, γ‐, and beyond, and the cycloaddition reaction of these species.