Assessment of Unconsciousness for Memory Consolidation Using EEG Signals

The assessment of consciousness and unconsciousness is a challenging issue in modern neuroscience. Consciousness is closely related to memory consolidation in that memory is a critical component of conscious experience. So far, many studies have been reported on memory consolidation during consciousness, but there is little research on memory consolidation during unconsciousness. Therefore, we aim to assess the unconsciousness in terms of memory consolidation using electroencephalogram signals. In particular, we used unconscious state during the nap; because sleep is the only state in which consciousness disappears under normal physiological conditions. Seven participants performed two memory tasks (word-pairs and visuo-spatial) before and after the nap to assess the memory consolidation during unconsciousness. As a result, spindle power in central, parietal, occipital regions during unconsciousness was positively correlated with the difference in location memory performance. With the difference in memory performance, there was also a negative correlation between delta connectivity and word-pairs memory, alpha connectivity and location memory, and spindle connectivity and word-pairs memory. Additionally, brain activity and connectivity for differences according to nap and unconsciousness during memory recall were explored. These findings could help present new insights into the assessment of unconsciousness by exploring the relationship with memory consolidation.