生物传感器
纳米纤维
生物分子
醋酸纤维素
膜
固定化酶
纳米技术
材料科学
纤维素
化学
酶
生物化学
作者
Xin Li,Quan Feng,Keyu Lu,Jia Huang,Yanan Zhang,Yue Hou,Hui Qiao,Dawei Li,Qufu Wei
标识
DOI:10.1016/j.bios.2020.112690
摘要
Development of reliable Enzymatic Biofuel Cells (EBFC)-based self-powered glucose biosensor for continuous, noninvasive monitoring without restriction on patient's movement is highly recommendable. However, its application to a large extent is limited by the relatively poor stability. Herein, we synthesized a highly flexible electrode for effective enzyme immobilization by encapsulating enzyme into the metal-organic frameworks (MOFs) and robustly anchored to the cellulose acetate (CA) nanofiber membrane. As is well-known, such nanostructured fiber materials are the first time to be synthesized for glucose biosensor, which encapsulated biomolecules in MOFs platform during the MOFs in-situ growth on the nanofiber membranes. The as-proposed biosensor demonstrated excellent stability over 15 h of continuous long-term monitoring. The remarkable stability of assembled self-powered glucose biosensor in this work could inspire the application of enzymatic biosensors in biometrics, chronic disease management and clinical diagnosis.
科研通智能强力驱动
Strongly Powered by AbleSci AI