Isolation, identification and in vivo antihypertensive effect of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Spirulina protein hydrolysate

By combining virtual screening and experimental assay, two angiotensin I-converting enzyme inhibitory peptides, TVLYEH and LQAGGLF, were identified from the protease K hydrolysate of Spirulina protein, and TVLYEH showed significantly antihypertensive effect in vivo .