Chemical constituents from rhizomes of Paeonia sinjiangensis

Objective To investigate the chemical constituents from the rhizomes of Paeonia sinjiangensis.Methods The chemical constituents were isolated and identified by chromatography on silica gel,Sephadex LH-20,ODS,and RP-HPLC.Their structures were elucidated on the basis of physicochemical properties and spectral analyses.Results Sixteen compounds were isolated from the 80% ethanol extract from the rhizomes of P.sinjiangensis,and identified as 8-debenzoylpaeoniflorin(1),4-O-butylpaeoniflorin(2),galloylpaeoniflorin(3),4-O-methylbenzoylpaeoniflorin(4),benzoylalbiflorin(5),albiflorin R1(6),9-O-butylpaeonidanin(7),(Z)-(1S,5R)-β-pinen-10-yl β-vicianoside(8),gallic acid(9),methyl gallate(10),ethyl gallate(11),isovanillic(12),6-hydroxycoumarin(13),3,4,23-trihydroxy-24,30-dinorolean-12,20(29)-dien-28-oic acid(14),palbinone(15),and cadina-4,11-dien-14-oic acid(16).Conclusion Compound 16 is firstly isolated from the Ranunculaceae family,and compounds 1—15 are isolated from this plant for the first time.