Review of the Preparation of Primary Amine from Carboxylic Acid

In this paper,various common methods to preparing primary amine from carboxylic acid were systematically summarized.They included primary amine prepared through amidation of carboxylic acid,carboxylic acid firstly reduced to alcohol,ketone and aldehydes and followed by ammonolysis for preparing primary amine,and direct conversion of carboxylic acid.Meanwhile,the advantages and problems existing in each method were pointed out.Finally,the preparation of primary amine from carboxylic acid were prospected.