Targeted and nontargated bone remodeling

The bone remodeling process as a means of bone metabolism is of fundamental importance both for the stability and integrity of bone,and for preventing the bone aging and repairing the damage of bone tissue.The form of purpose can be divided into targeted remodeling and nontargeted remodeling.In this paper,we aim to review the process and the communication with respect to these two kinds of bone remodeling as well as the effects of drugs on them.