In order to develop medical value of flavones active substance from persimmon leaves,in the paper,flavones were extracted from persimmon leaves using ethanol.Factors affecting the extracting rate were studied.Because rutin-Aluminum compound has the greatest absorption in 510 nm,flavones content were determined by spectrophotometer method.Effects of extraction time,extraction temperature,solid-liquid ratio and ethanol concentration on the obtaining rate of flavones were studied.The optimal extraction conditions were obtained through single factors and orthogonal experiments.The best parameters were as follows: extraction temperature at 80℃,extraction time 40min,70% ethanol concentration and the ratio of solid-liquid is 1:35.The obtaining rate of flavones from persimmon leaves is 5.76%.Among the conditions,affecting the extraction rate in turn is: extraction time extraction temperature solid-liquid ratio ethanol concentration.