Lycopene has very strong anti-oxidant ability, and can efficiently reduce the risk of many cancers,cardiovascular diseases,which makes lycopene well investigated.Due to its highly unsaturated structure,lycopene is easily degraded and isomerized.This paper reviewed recent researches on the stability of lycopene to heat,light,oxygen,and some additives.Microencapsulation of lycopene to improve lycopene stability was also mentioned.