This paper introduced the development of persistent organic pollutants(POPs)in the world,and described the distribution of persistent organic pollutants in typic area of our country,PAHs in middle and lower reaches of huai river was higher,and DDTs and PCBs were higher in Dalian lough than that in outer areas.POPs can be enriched in propagation continually.According to analysis,the BCF of POPs in fish was up to 1124.1,POPs was enriched by food chain,and brought tremendous threaten to ecosystem.As a result of persistent organic pollutants in recent years,death of animals and biological depopulation appeared in the world,persistent organic pollutants which were accumulated in bobies of human also influenced human health.At last,advices aimed at some problems at present and the tendency of development in this field in the future were presented.