白细胞介素2
混合淋巴细胞反应
免疫学
淋巴细胞
体外
T淋巴细胞
白细胞介素
化学
生物
T细胞
免疫系统
细胞因子
生物化学
作者
Jorma Ilonen,Riitta Karttunen
出处
期刊:Immunobiology
[Elsevier]
日期:1984-12-01
卷期号:167 (5): 399-403
被引量:6
标识
DOI:10.1016/s0171-2985(84)80072-8
摘要
Interleukin 2 (IL2) produced in vitro in mixed lymphocyte cultures was measured by induction of growth in cells dependent on IL2 for proliferation. The amount of IL2 in early cultures (24 and 48 hours) clearly differentiated the degree of HLA-D locus identity between various individuals. Very low amounts of IL2 were produced in cultures between HLA-D identical subjects. The use of IL2 measurement offers a method in the early culture phase for predicting the T cell proliferation which is dependent on the presence of IL2.
科研通智能强力驱动
Strongly Powered by AbleSci AI