*** Abstract. Using a numerical approach, the diversity, distribution and plant mass of aquatic macrophytes and helophytes from the Tisa river, in relation to river environmental conditions, were studied in 2004. Six aquatic macrophytes and 56 helophytes were detected. The plant mass of aquatic macrophytes was low and the distribution was limited to only some part of the river. The helophytes showed a better distribution at the whole river, but were dominated by only one mesohigrophyte - higrophyte species. The main environmental variables, identified as restricting the development of aquatic vegetation belong to following: water flow, depth and transparency for aquatic macrophytes and river bank structure for helophytes.