Safety evaluation of Rhizoma Dioscoreae bulbiferae and discussion risk control

Safety literatures on Rhizoma Dioscoreae bulbiferae and oral preparation have been reviewed and analyzed systematically, including textual research for origin and varieties, ancient and modern toxic record and toxic empirical study. Characteristics of clinical manifestations, risk factors and latest findings related to Rhizoma Dioscoreae bulbiferae have been concluded initially. The following measures may be effective for risk control and improving efficacy of Rhizoma Dioscoreae bulbiferae: to develope post-marketed evaluation actively; to regulate clinical medication; to strengthen safety-related basic study including the basis of toxic substances, toxic mechanism, efficacy enhancing and toxicity reducing etc.