Experiment research on hypericum perforatum of the anti-anoxi and anti-oxidative effect

Objective To investigate the anti-anoxi and anti-oxidative effect on hypericum perforatum.Methods 20 mices were randomly divided into normal group and hypericum perforatum group,each of 10 mices,Hypericum perforatum group were lavaged with hypericum perforatum,30 minutes later,observed the survival time of two groups mice under normal pressur and studied the anti-anoxi effect of hypericum perforatum; 30 SD rats were randomly divided into normal group,model group and hypericum perforatum group,each of 10 mices,the model of sub-acutely aging rats were made by D-gal,the rat in hypericum perforatum group were lavaged with hypericum perforatum once a day,after 30 days,detected CAT,SOD,GSH-Px,and MDA of every experimental group by biochemical method to study the anti-oxidative effect of hypericum perforatum. Results Hypericum perforatum count prolong mice anoxia survival time,increase the activities of CAT,SOD,GSH-Px evidently,and reduce the level of MDA in aging rats. Conclusion Hypericum perforatum has obviously anti-anoxia and anti-oxidative effect.