Study on reaction conditions of bionic synthesis of adipic acid from cyclohexane by catalytic oxidation with oxygen

One-pot liquid phase oxidation of cyclohexane to adipic acid with molecular oxygen catalyzed by meso-tetra (o-chlorophenyl) iron porphyrin(T(o-Cl)PPFe) under different conditions such as reaction temperature,reaction time,oxygen pressure and catalyst amount were studied.All parameters revealed significantly influence the yield of adipic acid and have optimal values respectively.T(o-Cl)PPFe was proved to be an excellent catalyst towards one-pot oxidation from cyclohexane to adipic acid favoring high turn over number (TON).Under the optimal reaction conditions like 140℃ of reaction temperature,25 MPa of reaction pressure,1.5 mg catalyst and 8 h of reaction time,the highest yield of adipic acid and TON were 21.4% and 24 582,respectively.