790P Extracellular traps of the circulating neutrophils in CIN and cervical cancer

Neutrophil Extracellular Traps (NET) participate in the implementation of the polarized neutrophils (Nph) pro-tumor function in various malignant neoplasms. Neutrophil elastase (NE) and interleukin-8 (CXCL8) regulate effector function of NET and are released in active form with NET to the extracellular space. The study was aimed to assess the levels of NE and CXCL8 in serum and Nph, and NET-forming function of Nph in CIN and cervical cancer (CC).