Kinetic Resolution of Oxiranes by Use of Chiral Lewis Acid Catalysts

All articles of this category The kinetic resolution of oxiranes by use of chiral Lewis acid catalysts is described. Improved stereoselectivities are observed in the nucleophilic ring opening of oxiranes with secondary amines. For the first time the enantioselective insertion of CO 2 into the oxirane ring forming enantiomerically enriched 1,3-dioxolanones was achieved applying chirally modified Zr- and Ti-complexes.