This paper describes the results of an experimental study of the behavior of the Friction Pendulum System in bridge seismic isolation. Earthquake simulator tests have been performed on a model bridge structure both isolated with Friction Pendulum System bearings and non-isolated. The experimental results demonstrate a marked increase of the capacity of the isolated bridge to withstand earthquake forces under all conditions. The frictional properties of the bearings remain markedly stable after extensive testing. Permanent displacements, which may develop in all hysteretic isolation systems, are found to be very small and not cumulative in successive earthquakes.