醇脱氢酶
还原酶
脱氢酶
生物催化
酶
辅因子
对映体
对映选择合成
固定化酶
对映体过量
还原（数学）
NAD+激酶
生物化学
选择性催化还原
作者
Federica Dall'Oglio,Martina Letizia Contente,Paola Conti,Francesco Molinari,Danila Monfredi,Andrea Pinto,Diego Romano,Daniela Ubiali,Lucia Tamborini,Immacolata Serra
标识
DOI：10.1016/j.catcom.2017.01.025
摘要
A robust two-enzyme system composed of an immobilized ketoreductase (KRED1-Pglu) and a glucose dehydrogenase (BmGDH) was developed via immobilization on aldehyde agarose for the stereoselective reduction of different ketones. The immobilized ketoreductase/glucose dehydrogenase system was continuously used in a flow reactor for weeks, even in the presence of concentrations of DMSO up to 20%.
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