伊布替尼
慢性淋巴细胞白血病
布鲁顿酪氨酸激酶
耐火材料(行星科学)
癌症研究
淋巴瘤
医学
白血病
肿瘤科
内科学
生物
受体
酪氨酸激酶
天体生物学
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2022-12-16
卷期号:13 (2): 252-252
标识
DOI:10.1158/2159-8290.cd-nb2022-0080
摘要
Abstract Results from ALPINE, a phase III trial, indicate that the second-generation BTK inhibitor zanubrutinib is superior to ibrutinib for patients with relapsed/refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. Besides having a better safety profile, zanubrutinib also improved progression-free survival.
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