Cyclopeptide Alkaloids and Vitamin C Derivatives with Antioxidant Activity from the Twigs of Antidesma fordii

Antidesma fordii Hemsl., a medicinal treelet native to southern China and Southeast Asia, has received limited scientific investigation despite its ethnopharmacological significance. This study reported the isolation of four previously unreported 4(14)‐integerrine‐type cyclopeptide alkaloids (1–4) and two vitamin C derivatives (5–6), along with the known compound scutianine M (7) from A. fordii twigs. The structures of compounds 1–6 were determined by spectroscopic data analysis, electronic circular dichroism (ECD) calculations, and X‐ray crystallography. Compound 5 displayed obvious antioxidant capacities in ABTS and FRAP assays. This study not only filled the phytochemical knowledge gap for A. fordii, but also identified the antioxidant potential of some compounds.