Interface‐Engineered CuxO@Bi2MoO6 Heterojunctions to Inhibit Piezoelectric Screening Effect and Promote Double‐Nanozyme Catalysis for Antibacterial Treatment

O with high selectivity. The heterojunction formation causes the transfer and rearrangement of interface electrons, and the increased piezopotential accelerates electron transfer at interfaces with bacteria, thus increasing the production of reactive oxidative species and interfering with adenosine triphosphate synthesis. The heterostructured nanozymes produce abundant intracellular ·OH and achieve 4log magnitude reductions in viable bacteria and effective biofilm dispersion. This study elucidates integral mechanisms of nanozyme and acoustic catalysis and opens up a new way to synergize high piezopotential and nanozyme-catalyzed therapy.