反应性(心理学)
分子间力
镍
化学
催化作用
酰胺
金属
氮气
立体化学
药物化学
分子
有机化学
病理
医学
替代医学
作者
Jinhong Chen,Hao Wang,Craig S. Day,Rubén Martı́n
标识
DOI:10.1002/anie.202212983
摘要
Abstract A nickel‐catalyzed site‐selective intermolecular amidation of saturated C(sp 3 )−H bonds is reported. This mild protocol exhibits a predictable reactivity pattern to incorporate amide functions at C(sp 3 )−H sites adjacent to nitrogen and oxygen atoms in either cyclic or acyclic frameworks, thus offering a complementary reactivity profile to existing oxidative‐type processes or metal‐catalyzed C(sp 3 )−N bond‐forming reactions operating via two‐electron manifolds.
科研通智能强力驱动
Strongly Powered by AbleSci AI