封锁
生物
癌症研究
黑色素瘤
免疫学
受体
遗传学
作者
Jeongsoo Kim,Tae‐Jin Kim,Sehyun Chae,Hyojeong Ha,Yejin Park,Sung Hee Park,Chul Joo Yoon,Seon Ah Lim,Hyemin Lee,Jiyoung Kim,Jungwon Kim,Kyungtaek Im,Kyunghye Lee,Jeongmin Kim,Daham Kim,Eun-Ju Lee,Min Hwa Shin,Serk In Park,Inmoo Rhee,Keehoon Jung
标识
DOI:10.1186/s12943-024-01936-w
摘要
In the myeloid compartment of the tumor microenvironment, CD244 signaling has been implicated in immunosuppressive phenotype of monocytes. However, the precise molecular mechanism and contribution of CD244 to tumor immunity in monocytes/macrophages remains elusive due to the co-existing lymphoid cells expressing CD244.
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