Experimental study on intracranial gadolinium deposition in rats after linear conversion to macrocyclic gadolinium contrast agent

To investigate the changes of intracranial gadolinium deposition in rats with linear gadolinium deposition after continuous injection of large ring gadolinium contrast agent. The intracranial gadolinium deposition in these rats increased but was relatively small. The DCN T1 value measured on MRI ensemble sequence scan images was significantly negatively correlated with gadolinium concentration in cerebellar DCN. (ALL P values were less than 0.05).