PCSK9
医学
动脉粥样硬化性心血管疾病
临床试验
前蛋白转化酶
阿利罗库单抗
可欣
安慰剂
药理学
药效学
疾病
药代动力学
胆固醇
重症监护医学
肿瘤科
生物信息学
内科学
低密度脂蛋白受体
脂蛋白
替代医学
病理
载脂蛋白A1
生物
作者
Fotios Barkas,Kausik K. Ray
标识
DOI:10.1080/14656566.2024.2337253
摘要
Inclisiran stands as a first-in-class breakthrough in lipid-lowering therapies, showing potential in alleviating the global burden of ASCVD and is supported by multiple global regulatory approvals. To optimize inclisiran's utilization and comprehend its long-term effects, future directions include pediatric studies, cardiovascular outcome trials, and extended-duration investigations. Overall, inclisiran emerges as a precise and effective therapeutic option, offering significant promise for preserving cardiovascular health.
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