Filtrates from certain liquid cultures of Chlorella vulgaris (Columbian strain) developed sufficient peroxide content, after a few days’ storage, to inhibit further growth of Chlorella when they were used to prepare fresh culture media. Similar inhibition was observed when Chlorella was cultured in media containing various added organic peroxides. Growth of Chlorella was not limited by autoinhibitor production under the conditions employed, and no peroxide or other inhibitor was detected in solvent extracts of the cells or fresh filtrates.