NAC transcription factors: structurally distinct, functionally diverse

NAC proteins constitute one of the largest families of plant-specific transcription factors, and the family is present in a wide range of land plants. Here, we summarize the biological and molecular functions of the NAC family, paying particular attention to the intricate regulation of NAC protein level and localization, and to the first indications of NAC participation in transcription factor networks. The recent determination of the DNA and protein binding NAC domain structure offers insight into the molecular functions of the protein family. Research into NAC transcription factors has demonstrated the importance of this protein family in the biology of plants and the need for further studies. NAC proteins constitute one of the largest families of plant-specific transcription factors, and the family is present in a wide range of land plants. Here, we summarize the biological and molecular functions of the NAC family, paying particular attention to the intricate regulation of NAC protein level and localization, and to the first indications of NAC participation in transcription factor networks. The recent determination of the DNA and protein binding NAC domain structure offers insight into the molecular functions of the protein family. Research into NAC transcription factors has demonstrated the importance of this protein family in the biology of plants and the need for further studies. abscisic acid. AUXIN-INDUCED IN ROOT CULTURES 3, a subtilisin-like protease. Arabidopsis NAC protein. Arabidopsis NAC protein 019, previously called ANAC. Arabidopsis NAC protein 055. Arabidopsis NAC protein 072, also called RD26. APETALA 3, a MADS box transcription factor. AUXIN RESPONSE FACTOR. ASYMMETRIC1, a MYB domain transcription factor. ASYMMETRIC2, a lateral organ boundaries-domain protein. auxin/indole-3-acetic acid. Brassica napus NAC. cauliflower mosaic virus. capsid protein. CUP-SHAPED COTYLEDON 1, a NAC protein. CUP-SHAPED COTYLEDON 2, a NAC protein. CUP-SHAPED COTYLEDON 3, a NAC protein. CUC1 mutant alleles. CUPULIFORMIS, a NAC protein. DNA-BINDING PROTEIN. EARLY RESPONSIVE TO DEHYDRATION STRESS 1, a protein with homology to protease subunit. expressed sequence tag. glial cells missing, a transcription factor family. glyoxalase I family protein. geminivirus RepA-binding protein, a NAC protein. geminivirus RepA-binding protein, a NAC protein. HvSPY-interacting NAC, a NAC protein. Hordeum vulgare SPINDLY, a negative regulator of gibberellin responses. KNOTTED 1-like homeobox. MCM1, AGAMOUS, DEFICIENS and SRF. microRNA. MONOPTEROS, an ARF transcription factor. myeloblastosis, a transcription factor family. NAM, ATAF1,2, CUC2. no apical meristem, a NAC protein. NAC-like, activated by APETALA 3/PISTILLATA. nuclear export signal. nuclear localization signal. NAM-related protein 1, a NAC protein. Oryza sativa NAC. PISTILLATA, a MADS box transcription factor. PINOID, a serine/threonine kinase. PIN-FORMED 1, a putative auxin efflux regulator. RESPONSIVE TO DESICCATION 26, also called ANAC072. really interesting new gene, a conserved zinc-finger motif. shoot apical meristem. Skp1, Cullin, F-box E3 complex. SINA of Arabidopsis thaliana 5, a RING protein. SHOOT MERISTEMLESS, a KNOX protein. Solanum tuberosum NAC, a NAC protein. TB1, CYC, PCF, a transcription factor family. turnip crinkle virus. TCV-interacting protein. transport inhibitor response 1, an F-box protein.