Outer Membrane Vesicle-Host Cell Interactions

Outer membrane vesicles (OMVs) are nanosized, spherical proteoliposomes. They are secreted via vesiculation of the outer membrane by Gram-negative bacteria as part of the normal growth process (1). OMVs play diverse roles in intracellular communication, microbial virulence, and modulation of the host immune response (2).