Circular biomanufacturing through harvesting solar energy and CO2

Earth receives 5000× more solar energy than required to power the entire global economy. The biosynthetic capacity of the chloroplast and catalytic versatility of P450 enzymes enables sustainable production of numerous high-value compounds and bulk products. The global supply of low-emission fuels may be supplied by microalgae grown on floating ocean platforms covering 0.2–0.3% of Earth’s surface. Development of environmentally benign photosynthesis-based advanced production systems build on cross-disciplinary research, open mindedness, and a willingness to share will foster biophilicity and thus increase societal awareness of nature. Researchers, governments, and industry have the tools in place to power a sustainable solar biotechnology (Я)evolution. Knowledge-based political leadership is now critical to support scale up and ensure economic, social, and environmental security. Using synthetic biology, it is now time to expand the biosynthetic repertoire of plants and microalgae by utilizing the chloroplast to augment the production of desired high-value compounds and of oil-, carbohydrate-, or protein-enriched biomass based on direct harvesting of solar energy and the consumption of CO2. Multistream product lines based on separate commercialization of the isolated high-value compounds and of the improved bulk products increase the economic potential of the light-driven production system and accelerate commercial scale up. Here we outline the scientific basis for the establishment of such green circular biomanufacturing systems and highlight recent results that make this a realistic option based on cross-disciplinary basic and applied research to advance long-term solutions. Using synthetic biology, it is now time to expand the biosynthetic repertoire of plants and microalgae by utilizing the chloroplast to augment the production of desired high-value compounds and of oil-, carbohydrate-, or protein-enriched biomass based on direct harvesting of solar energy and the consumption of CO2. Multistream product lines based on separate commercialization of the isolated high-value compounds and of the improved bulk products increase the economic potential of the light-driven production system and accelerate commercial scale up. Here we outline the scientific basis for the establishment of such green circular biomanufacturing systems and highlight recent results that make this a realistic option based on cross-disciplinary basic and applied research to advance long-term solutions. plants produce a plethora of specialized metabolites to adapt to environmental challenges and to communicate with the environment. Bioactive natural products are utilized by humans in all aspects of daily life (e.g., as medicines, stimulants, colorants, flavors, and condiments). the use of biological organisms to facilitate the sustainable production of a wide variety of compounds and materials inspired by natural principles. production systems focused on sustainable, resource-efficient valorization of biomass in integrated, multioutput production chains (e.g., biorefineries) while also making use of residues and wastes and optimizing the value of biomass over time via cascading. the sixth IPCC assessment report delivered by the United Nations secretary in August 2021 is called Code red for humanity because it predicts a scenario where the Earth’s temperature will rise to unprecedented levels. Action is needed now is the conclusion. after World War II, the implementation of agricultural technologies led to an increase in agricultural production in the late 1960s, as an outcome of a set of research technology transfers occurring in the 1950s to the late 1960s. the United Nations body that assesses the science related to climate change. The IPCC was created to support political decision making by providing regular scientific assessment on climate change; the latest report was published in August 2021.