Case 27

Abstract Mononeuropathy multiplex is a disorder which distinguishes itself from peripheral polyneuropathy by involvement of specific individual peripheral nerves. Mononeuropathy multiplex is often asymmetrical and is classified, based on electrophysiologic and pathologic findings, into axonal and demyelinating types. Mononeuritis multiplex is a term that is used exclusively for cases of axonal multiple mononeuropathies due to peripheral nerve vasculitis. This may be associated with connective tissue disease or hepatitis B and C infection. This case outlines the clinical and electrophysiological findings in mononeuritis multiplex and discusses the differential diagnosis of systemic and nonsystemic vasculitic neuropathy. The causes and pathological findings that characterize vasculitic neuropathy are highlighted.